Both pilots were able to eject safely from the aircraft, according to an Air Force press release.
The aircraft crashed at about 8:30 a.m. Wednesday in a remote area near Columbus Air Force Base.
Local law enforcement and first responders arrived on the scene shortly after the crash and both pilots were transported to a local hospital for evaluation.
The first responders were able to extinguish a fire that resulted from the impact, and secured the area, according to base officials.
There are no houses or other structures in the immediate area of the crash, according to the Air Force.